|T000070, PIM Tracer
Compound Image

T000070

PIM Tracer

  • Description

    Formula:

    C43H42BF5N8O3

    avg. MolWt:

    824.66 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm

    clogP:

    7.34
  • References

    Contributing Lab:

    Promega Corp., Madison

  • Experimental

    : 9.29

    Z’: 0.86

    : yes

    Tracer titration

    KDapp:

    111 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    PIM447

    EC50:

    10 nM
    raw data

    Comment: PIM1-NLuc

    : 4.35

    Z’: 0.9

    : yes

    Tracer titration

    KDapp:

    1532 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    PIM447

    EC50:

    22 nM
    raw data

    Comment: PIM2-NLuc

    : 3.25

    Z’: 0.91

    : yes

    Tracer titration

    KDapp:

    150 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    PIM447

    EC50:

    5 nM
    raw data

    Comment: NLuc-PIM3