|T000066, SHP2 (PTPN11) Tracer (PBI 9006)
Compound Image

T000066

SHP2 (PTPN11) Tracer (PBI 9006)

  • Description

    Formula:

    C38H41BCl2F2N12O

    avg. MolWt:

    801.54 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm

    clogP:

    5.69
  • References

    Contributing Lab:

    Promega Corp., Madison

  • Experimental

    : 3.4

    Z’: 0.88

    : yes

    Tracer titration

    KDapp:

    507 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    SHP099

    EC50:

    116 nM
    raw data

    Comment: NLuc-SHP2(PTPN11)