Formula:
avg. MolWt:
PAINS elements:
SMILES:
O=C1NC2=C(C(C3=CC=C([C@@H](C)CNC(CCC4=CC=C5N4[B-](F)(F)[N+]6=C(C7=CC=CN7)C=CC6=C5)=O)C=C3)=C(O)C=C2C)C8=C1SC=C8
Store at:
Absorption:
Emission:
clogP:
Contributing Lab:
Knapp Lab, University of Frankfurt
: 2.2
Z’: 0.59
: yes
KDapp:
Compound used for displacement:
OTS964
EC50:
Comment: NLuc-CDK19 + CycL2
: 1.52
Z’: 0.54
Dinaciclib
Comment: NLuc-CDK9 without Cyclin activation