|T000061, K12 Tracer

Compound Image

T000061

K12 Tracer

Properties

Store at:

-80 °C

Absorption:

450 nm

Emission:

590 nm
References

Contributing Lab:

Promega Corp., Madison

Vendor:

Promega
Experimental

: 4.2

Z’: 0.82

: yes

Tracer titration

KD_app:

105 nM

raw data

Tracer displacement

i

Compound used for displacement:

Dinaciclib

EC₅₀:

584 nM

raw data

Comment: CDK1-NLuc + CycB1

Reference: source

: 3.7

Z’: 0.81

: yes

Tracer titration

KD_app:

157 nM

raw data

Tracer displacement

i

Compound used for displacement:

Dinaciclib

EC₅₀:

177 nM

raw data

Comment: CDK1-NLuc + CycE1

Reference: source

: 3.92

Z’: 0.75

: yes

Tracer titration

KD_app:

212 nM

raw data

Tracer displacement

i

Compound used for displacement:

SNS-032

EC₅₀:

989 nM

raw data

Comment: CDK10-NLuc + CycL2

Reference: source

: 4.07

Z’: 0.9

: yes

Tracer titration

KD_app:

217 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

165 nM

raw data

Comment: CDK11A-NLuc + CycK

Reference: source

: 4.66

Z’: 0.88

: yes

Tracer titration

KD_app:

137 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

278 nM

raw data

Comment: CDK11B-NLuc + CycL2

Reference: source

: 5.22

Z’: 0.64

: yes

Tracer titration

KD_app:

92 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

306 nM

raw data

Comment: CDK14-NLuc + CycY

Reference: source

: 3.9

Z’: 0.71

: yes

Tracer titration

KD_app:

40 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

185 nM

raw data

Comment: NLuc-CDK15 + CycY

Reference: source

: 4.11

Z’: 0.71

: yes

Tracer titration

KD_app:

146 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

42 nM

raw data

Comment: CDK16-NLuc + CycY

Reference: source

: 4.26

Z’: 0.74

: yes

Tracer titration

KD_app:

121 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

51 nM

raw data

Comment: CDK17-NLuc + CycY

Reference: source

: 7.53

Z’: 0.76

: yes

Tracer titration

KD_app:

126 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

467 nM

raw data

Comment: CDK18-NLuc + CycY

Reference: source

: 4.64

Z’: 0.86

: yes

Tracer titration

KD_app:

164 nM

raw data

Tracer displacement

i

Compound used for displacement:

AT7519

EC₅₀:

2 µM

raw data

Comment: CDK3-NLuc + CycE1

Reference: source

: 3.75

Z’: 0.9

: yes

Tracer titration

KD_app:

127 nM

raw data

Tracer displacement

i

Compound used for displacement:

Palbociclib

EC₅₀:

33 nM

raw data

Comment: NLuc-CDK4 + CycD1

Reference: source

: 5.16

Z’: 0.77

: yes

Tracer titration

KD_app:

88 nM

raw data

Tracer displacement

i

Compound used for displacement:

Abemaciclib

EC₅₀:

2 nM

raw data

Comment: NLuc-CDK4 + CycD3

Reference: source

: 3.53

Z’: 0.82

: yes

Tracer titration

KD_app:

77 nM

raw data

Tracer displacement

i

Compound used for displacement:

Dinaciclib

EC₅₀:

734 nM

raw data

Comment: NLuc-CDK7 + pGEM

Reference: source

: 11.59

Z’: 0.93

: yes

Tracer titration

KD_app:

13 nM

raw data

Tracer displacement

i

Compound used for displacement:

Dinaciclib

EC₅₀:

11 nM

raw data

Comment: NLuc-CDK9 + CycK

Reference: source