|T000039, K11 Tracer

Compound Image

T000039

K11 Tracer

Properties

Store at:

-80 °C

Absorption:

450 nm

Emission:

590 nm
References

Contributing Lab:

Promega Corp., Madison

Vendor:

Promega
Experimental

: 3.52

Z’: 0.76

: yes

Tracer titration

KD_app:

220 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

51 nM

raw data

Comment: ACVR1-NLuc

Reference: source

: 4.3

Z’: 0.69

: yes

Tracer titration

KD_app:

327 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

33 nM

raw data

Comment: ACVR1(G328V)

Reference: source

: 3.62

Z’: 0.75

: yes

Tracer titration

KD_app:

520 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

129 nM

raw data

Comment: ACVR1(G356D)-NLuc

Reference: source

: 3.79

Z’: 0.81

: yes

Tracer titration

KD_app:

402 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

51 nM

raw data

Comment: ACVR1(Q207D)

Reference: source

: 3.59

Z’: 0.75

: yes

Tracer titration

KD_app:

388 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

41 nM

raw data

Comment: ACVR1(R206H)-NLuc

Reference: source

: 3.31

Z’: 0.88

: yes

Tracer titration

KD_app:

184 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

378 nM

raw data

Comment: ACVRL1-NLuc

Reference: source

: 2.25

Z’: 0.75

: yes

Tracer titration

KD_app:

252 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

113 nM

raw data

Comment: BMPR1A-NLuc

Reference: source

: 3.09

Z’: 0.75

: yes

Tracer titration

KD_app:

231 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

34 nM

raw data

Comment: NLuc-CDKL1

Reference: source

: 10.69

Z’: 0.85

: yes

Tracer titration

KD_app:

387 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

5 nM

raw data

Comment: NLuc-CDKL2

Reference: source

: 7.81

Z’: 0.84

: yes

Tracer titration

KD_app:

196 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

5 nM

raw data

Comment: NLuc-CDKL3

Reference: source

: 7.81

Z’: 0.76

: yes

Tracer titration

KD_app:

303 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

2 nM

raw data

Comment: NLuc-CDKL5

Reference: source

: 2.99

Z’: 0.83

: yes

Tracer titration

KD_app:

267 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

122 nM

raw data

Comment: EPHA3-NLuc

Reference: source

: 2.13

Z’: 0.87

: yes

Tracer titration

KD_app:

33 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

524 nM

raw data

Comment: MAP2K6-NLuc

Reference: source

: 2.17

Z’: 0.81

: yes

Tracer titration

KD_app:

105 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

8 µM

raw data

Comment: NLuc-NRK

Reference: source

: 3.43

Z’: 0.94

: yes

Tracer titration

KD_app:

178 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

180 nM

raw data

Comment: TGFBR2-NLuc

Reference: source