|T000038, K8 Tracer

Compound Image

T000038

K8 Tracer

Properties

Store at:

-80 °C

Absorption:

450 nm

Emission:

590 nm
References

Contributing Lab:

Promega Corp., Madison

Vendor:

Promega
Experimental

: 2.84

Z’: 0.85

: yes

Tracer titration

KD_app:

140 nM

raw data

Tracer displacement

i

Compound used for displacement:

ABT-702

EC₅₀:

5 nM

raw data

Comment: ADK-NLuc

Reference: source

: 2.23

Z’: 0.87

: yes

Tracer titration

KD_app:

21 nM

raw data

Tracer displacement

i

Compound used for displacement:

AST-487

EC₅₀:

13 nM

raw data

Comment: NLuc-CDK19 + CycC

Reference: source

: 2.52

Z’: 0.9

: yes

Tracer titration

KD_app:

22 nM

raw data

Tracer displacement

i

Compound used for displacement:

AST-487

EC₅₀:

38 nM

raw data

Comment: NLuc-CDK8 + CycC

Reference: source

: 6.73

Z’: 0.74

: yes

Tracer titration

KD_app:

43 nM

raw data

Tracer displacement

i

Compound used for displacement:

Dinaciclib

EC₅₀:

12 nM

raw data

Comment: NLuc-CDK9 + CycK

Reference: source

: 4.02

Z’: 0.79

: yes

Tracer titration

KD_app:

69 nM

raw data

Tracer displacement

i

Compound used for displacement:

Dinaciclib

EC₅₀:

16 nM

raw data

Comment: NLuc-CDK9 + CycT1

Reference: source

: 3.21

Z’: 0.86

: yes

Tracer titration

KD_app:

72 nM

raw data

Tracer displacement

i

Compound used for displacement:

CEP-701

EC₅₀:

757 nM

raw data

Comment: NLuc-ICK

: 5.14

Z’: 0.8

: yes

Tracer titration

KD_app:

124 nM

raw data

Tracer displacement

i

Compound used for displacement:

AZD-5438

EC₅₀:

1 µM

raw data

Comment: NLuc-CSNK1D

Reference: source

: 2.54

Z’: 0.85

: yes

Tracer titration

KD_app:

154 nM

raw data

Tracer displacement

i

Compound used for displacement:

AZD-5438

EC₅₀:

4 µM

raw data

Comment: NLuc-CSNK1E

Reference: source

: 3.38

Z’: 0.64

: yes

Tracer titration

KD_app:

94 nM

raw data

Tracer displacement

i

Compound used for displacement:

CHIR-99021

EC₅₀:

55 nM

raw data

Comment: NLuc-GSK3A

Reference: source

: 7.43

Z’: 0.77

: yes

Tracer titration

KD_app:

94 nM

raw data

Tracer displacement

i

Compound used for displacement:

CHIR-99021

EC₅₀:

120 nM

raw data

Comment: NLuc-GSK3B

Reference: source

: 2.55

Z’: 0.71

: yes

Tracer titration

KD_app:

78 nM

raw data

Tracer displacement

i

Compound used for displacement:

CEP-701

EC₅₀:

419 nM

raw data

Comment: KIT(V559D,T670I)-NLuc

Reference: source

: 2.63

Z’: 0.75

: yes

Tracer titration

KD_app:

55 nM

raw data

Tracer displacement

i

Compound used for displacement:

PBI-7210

EC₅₀:

89 nM

raw data

Comment: PIKFYVE-NLuc

Reference: source

: 3.14

Z’: 0.72

: yes

Tracer titration

KD_app:

117 nM

raw data

Tracer displacement

i

Compound used for displacement:

PBI-7210

EC₅₀:

99 nM

raw data

Comment: PIP4K2C-NLuc

Reference: source

: 2.5

Z’: 0.74

: yes

Tracer titration

KD_app:

54 nM

raw data

Tracer displacement

i

Compound used for displacement:

PBI-7210

EC₅₀:

3 µM

raw data

Comment: NLuc-PIP5K1B

Reference: source

: 2.79

Z’: 0.84

: yes

Tracer titration

KD_app:

72 nM

raw data

Tracer displacement

i

Compound used for displacement:

APY-69

EC₅₀:

972 nM

raw data

Comment: NLuc-RIPK1

Reference: source