|T000037, K4 Tracer
Compound Image

T000037

K4 Tracer


  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm
  • References

    Contributing Lab:

    Promega Corp., Madison

    Vendor:

  • Experimental

    : 2.7

    Z’: 0.91

    : yes

    Tracer titration

    KDapp:

    63 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    3 nM
    raw data

    Comment: NLuc-ABL1

    Reference: source

    : 2.82

    Z’: 0.63

    : yes

    Tracer titration

    KDapp:

    125 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    25 nM
    raw data

    Comment: NLuc-ABL1(E255K)

    Reference: source

    : 2.82

    Z’: 0.53

    : yes

    Tracer titration

    KDapp:

    127 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    17 nM
    raw data

    Comment: NLuc-ABL1(F317I)

    Reference: source

    : 3.66

    Z’: 0.65

    : yes

    Tracer titration

    KDapp:

    21 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    8 nM
    raw data

    Comment: NLuc-ABL1(H396P)

    Reference: source

    : 3.25

    Z’: 0.9

    : yes

    Tracer titration

    KDapp:

    44 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    13 nM
    raw data

    Comment: NLuc-ABL1(M351T)

    Reference: source

    : 3.5

    Z’: 0.92

    : yes

    Tracer titration

    KDapp:

    39 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    14 nM
    raw data

    Comment: NLuc-ABL1(Q252H)

    Reference: source

    : 3.09

    Z’: 0.76

    : yes

    Tracer titration

    KDapp:

    43 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    15 nM
    raw data

    Comment: NLuc-ABL1(Y253F)

    Reference: source

    : 7.2

    Z’: 0.81

    : yes

    Tracer titration

    KDapp:

    8 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    6 nM
    raw data

    Comment: NLuc-ABL2

    Reference: source

    : 4.83

    Z’: 0.85

    : yes

    Tracer titration

    KDapp:

    139 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    3 nM
    raw data

    Comment: NLuc-BLK

    Reference: source

    : 6.95

    Z’: 0.51

    : yes

    Tracer titration

    KDapp:

    262 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    3 nM
    raw data

    Comment: BMX-NLuc

    Reference: source

    : 2.35

    Z’: 0.74

    : yes

    Tracer titration

    KDapp:

    111 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    8 nM
    raw data

    Comment: CSF1R-NLuc

    Reference: source

    : 3.76

    Z’: 0.6

    : yes

    Tracer titration

    KDapp:

    611 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    18 nM
    raw data

    Comment: CSK-NLuc

    Reference: source

    : 9.62

    Z’: 0.83

    : yes

    Tracer titration

    KDapp:

    22 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    2 nM
    raw data

    Comment: DDR1-NLuc

    Reference: source

    : 4.37

    Z’: 0.71

    : yes

    Tracer titration

    KDapp:

    70 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    2 nM
    raw data

    Comment: DDR2-NLuc

    Reference: source

    : 4.32

    Z’: 0.78

    : yes

    Tracer titration

    KDapp:

    62 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    3 nM
    raw data

    Comment: DDR2(N456S)-NLuc

    Reference: source

    : 4.05

    Z’: 0.79

    : yes

    Tracer titration

    KDapp:

    177 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    3 nM
    raw data

    Comment: EPHA1-NLuc

    Reference: source

    : 5.92

    Z’: 0.74

    : yes

    Tracer titration

    KDapp:

    41 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    2 nM
    raw data

    Comment: EPHA2-NLuc

    Reference: source

    : 8.37

    Z’: 0.85

    : yes

    Tracer titration

    KDapp:

    28 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    1 nM
    raw data

    Comment: EPHA4-NLuc

    Reference: source

    : 6.97

    Z’: 0.83

    : yes

    Tracer titration

    KDapp:

    23 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    1 nM
    raw data

    Comment: EPHA5-NLuc

    Reference: source

    : 9.03

    Z’: 0.66

    : yes

    Tracer titration

    KDapp:

    7 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    2 nM
    raw data

    Comment: EPHA8-NLuc

    Reference: source

    : 6.1

    Z’: 0.81

    : yes

    Tracer titration

    KDapp:

    13 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    4 nM
    raw data

    Comment: EPHB2-NLuc

    Reference: source

    : 4.47

    Z’: 0.74

    : yes

    Tracer titration

    KDapp:

    87 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    5 nM
    raw data

    Comment: EPHB3-NLuc

    Reference: source

    : 5.63

    Z’: 0.74

    : yes

    Tracer titration

    KDapp:

    6 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    1 nM
    raw data

    Comment: EPHB4-NLuc

    Reference: source

    : 4.14

    Z’: 0.83

    : yes

    Tracer titration

    KDapp:

    207 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    25 nM
    raw data

    Comment: NLuc-FGR

    Reference: source

    : 2.65

    Z’: 0.72

    : yes

    Tracer titration

    KDapp:

    142 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    30 nM
    raw data

    Comment: FRK-NLuc

    Reference: source

    : 5.39

    Z’: 0.84

    : yes

    Tracer titration

    KDapp:

    219 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    3 nM
    raw data

    Comment: FYN-NLuc

    Reference: source

    : 6.35

    Z’: 0.87

    : yes

    Tracer titration

    KDapp:

    17 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    2 nM
    raw data

    Comment: FYN(Y531F)-NLuc

    Reference: source

    : 2.9

    Z’: 0.61

    : yes

    Tracer titration

    KDapp:

    375 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Bosutinib

    EC50:

    3 µM
    raw data

    Comment: HCK-NLuc

    Reference: source

    : 2.64

    Z’: 0.62

    : yes

    Tracer titration

    KDapp:

    59 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    49 nM
    raw data

    Comment: KIT-NLuc

    Reference: source

    : 2.4

    Z’: 0.64

    : yes

    Tracer titration

    KDapp:

    209 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    34 nM
    raw data

    Comment: KIT(A829P)-NLuc

    Reference: source

    : 2.22

    Z’: 0.75

    : yes

    Tracer titration

    KDapp:

    327 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    62 nM
    raw data

    Comment: KIT(D816H)-NLuc

    Reference: source

    : 3.37

    Z’: 0.85

    : yes

    Tracer titration

    KDapp:

    130 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    17 nM
    raw data

    Comment: KIT(L576P)-NLuc

    Reference: source

    : 4.35

    Z’: 0.84

    : yes

    Tracer titration

    KDapp:

    24 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    5 nM
    raw data

    Comment: KIT(V559D)-NLuc

    Reference: source

    : 2.25

    Z’: 0.7

    : yes

    Tracer titration

    KDapp:

    358 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    117 nM
    raw data

    Comment: KIT (V559D,V654A)-NLuc

    Reference: source

    : 4.72

    Z’: 0.86

    : yes

    Tracer titration

    KDapp:

    18 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    25 nM
    raw data

    Comment: LCK-NLuc

    Reference: source

    : 3.93

    Z’: 0.8

    : yes

    Tracer titration

    KDapp:

    35 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    10 nM
    raw data

    Comment: LYN-NLuc

    Reference: source

    : 4.26

    Z’: 0.8

    : yes

    Tracer titration

    KDapp:

    230 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Nilotinib

    EC50:

    15 nM
    raw data

    Comment: NLuc-MAPK11

    Reference: source

    : 3.8

    Z’: 0.63

    : yes

    Tracer titration

    KDapp:

    111 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    455 nM
    raw data

    Comment: MAPK14-NLuc

    Reference: source

    : 2.23

    Z’: 0.78

    : yes

    Tracer titration

    KDapp:

    107 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    4 nM
    raw data

    Comment: PDGFRA(V561D)-NLuc

    Reference: source

    : 3.02

    Z’: 0.63

    : yes

    Tracer titration

    KDapp:

    481 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    63 nM
    raw data

    Comment: PTK6-NLuc

    Reference: source

    : 3.47

    Z’: 0.66

    : yes

    Tracer titration

    KDapp:

    112 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    1 nM
    raw data

    Comment: NLuc-RIPK2

    Reference: source

    : 6.92

    Z’: 0.79

    : yes

    Tracer titration

    KDapp:

    118 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    5 nM
    raw data

    Comment: NLuc-SIK1

    Reference: source

    : 6.65

    Z’: 0.76

    : yes

    Tracer titration

    KDapp:

    157 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    7 nM
    raw data

    Comment: NLuc-SIK2

    Reference: source

    : 4.0

    Z’: 0.8

    : yes

    Tracer titration

    KDapp:

    549 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    72 nM
    raw data

    Comment: NLuc-SIK3

    Reference: source

    : 5.3

    Z’: 0.74

    : yes

    Tracer titration

    KDapp:

    138 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    18 nM
    raw data

    Comment: SRC-NLuc

    Reference: source

    : 5.84

    Z’: 0.92

    : yes

    Tracer titration

    KDapp:

    477 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    258 nM
    raw data

    Comment: NLuc-TEC

    Reference: source

    : 2.54

    Z’: 0.74

    : yes

    Tracer titration

    KDapp:

    506 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    680 nM
    raw data

    Comment: NLuc-TESK1

    Reference: source

    : 3.89

    Z’: 0.7

    : yes

    Tracer titration

    KDapp:

    145 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    19 nM
    raw data

    Comment: TXK-NLuc

    Reference: source

    : 2.64

    Z’: 0.63

    : yes

    Tracer titration

    KDapp:

    345 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Dasatinib

    EC50:

    24 nM
    raw data

    Comment: YES1-NLuc

    Reference: source