Store at:
Absorption:
Emission:
Contributing Lab:
Promega Corp., Madison
Vendor:
: 2.7
Z’: 0.91
: yes
KDapp:
Compound used for displacement:
Dasatinib
EC50:
Comment: NLuc-ABL1
Reference: source
: 2.82
Z’: 0.63
Comment: NLuc-ABL1(E255K)
Z’: 0.53
Comment: NLuc-ABL1(F317I)
: 3.66
Z’: 0.65
Comment: NLuc-ABL1(H396P)
: 3.25
Z’: 0.9
Comment: NLuc-ABL1(M351T)
: 3.5
Z’: 0.92
Comment: NLuc-ABL1(Q252H)
: 3.09
Z’: 0.76
Comment: NLuc-ABL1(Y253F)
: 7.2
Z’: 0.81
Comment: NLuc-ABL2
: 4.83
Z’: 0.85
Comment: NLuc-BLK
: 6.95
Z’: 0.51
Comment: BMX-NLuc
: 2.35
Z’: 0.74
Comment: CSF1R-NLuc
: 3.76
Z’: 0.6
Comment: CSK-NLuc
: 9.62
Z’: 0.83
Comment: DDR1-NLuc
: 4.37
Z’: 0.71
Comment: DDR2-NLuc
: 4.32
Z’: 0.78
Comment: DDR2(N456S)-NLuc
: 4.05
Z’: 0.79
Comment: EPHA1-NLuc
: 5.92
Comment: EPHA2-NLuc
: 8.37
Comment: EPHA4-NLuc
: 6.97
Comment: EPHA5-NLuc
: 9.03
Z’: 0.66
Comment: EPHA8-NLuc
: 6.1
Comment: EPHB2-NLuc
: 4.47
Comment: EPHB3-NLuc
: 5.63
Comment: EPHB4-NLuc
: 4.14
Comment: NLuc-FGR
: 2.65
Z’: 0.72
Comment: FRK-NLuc
: 5.39
Z’: 0.84
Comment: FYN-NLuc
: 6.35
Z’: 0.87
Comment: FYN(Y531F)-NLuc
: 2.9
Z’: 0.61
Bosutinib
Comment: HCK-NLuc
: 2.64
Z’: 0.62
Comment: KIT-NLuc
: 2.4
Z’: 0.64
Comment: KIT(A829P)-NLuc
: 2.22
Z’: 0.75
Comment: KIT(D816H)-NLuc
: 3.37
Comment: KIT(L576P)-NLuc
: 4.35
Comment: KIT(V559D)-NLuc
: 2.25
Z’: 0.7
Comment: KIT (V559D,V654A)-NLuc
: 4.72
Z’: 0.86
Comment: LCK-NLuc
: 3.93
Z’: 0.8
Comment: LYN-NLuc
: 4.26
Nilotinib
Comment: NLuc-MAPK11
: 3.8
Comment: MAPK14-NLuc
: 2.23
Comment: PDGFRA(V561D)-NLuc
: 3.02
Comment: PTK6-NLuc
: 3.47
Comment: NLuc-RIPK2
: 6.92
Comment: NLuc-SIK1
: 6.65
Comment: NLuc-SIK2
: 4.0
Comment: NLuc-SIK3
: 5.3
Comment: SRC-NLuc
: 5.84
Comment: NLuc-TEC
: 2.54
Comment: NLuc-TESK1
: 3.89
Comment: TXK-NLuc
Comment: YES1-NLuc