|T000036, Palbociclib-FITC
Compound Image

T000036

Palbociclib-FITC

  • Description

    Formula:

    C51H53N9O7S

    avg. MolWt:

    936.11 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -20 °C

    Absorption:

    475 nm

    Emission:

    520 nm

    clogP:

    8.51
  • References

    Synthesis:

    Publication

    Contributing Lab:

    Mazitschek Lab, Massachusetts General Hospital, Boston and Woo Lab, Harvard University, Boston

  • Experimental

    : 33.6

    Z’: 0.91

    : yes

    Tracer titration

    KD:

    6 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    dCDK-1

    IC50:

    54 nM
    raw data

    Comment: 1 nM CoraFluor-1-labeled anti-His6 antibody; 2 nM His6-GST-CDK4/GST-CD3

    Reference: PMID

    : 23.4

    Z’: 0.87

    : yes

    Tracer titration

    KD:

    263 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    dCDK-1

    IC50:

    338 nM
    raw data

    Comment: 1 nM CoraFluor-1-labeled anti-His6 antibody; 2 nM His6-CDK6/GST-CD1

    Reference: PMID