|T000035, SLF-FITC
Compound Image

T000035

SLF-FITC

  • Description

    Formula:

    C61H69N5O15S

    avg. MolWt:

    1144.31 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -20 °C

    Absorption:

    475 nm

    Emission:

    520 nm

    clogP:

    8.44
  • References

    Synthesis:

    Publication

    Contributing Lab:

    Mazitschek Lab, Massachusetts General Hospital, Boston and Woo Lab, Harvard University, Boston

  • Experimental

    Assay window 19.9
    \(Z'\) 0.86
    CP agreement yes
    Tracer titration

    \(K_\mathrm{D}\):

    37 nM
    titration curve
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    d-FKPB1

    \(\mathrm{IC}_{50}\):

    32 nM
    displacement curve
    raw data

    Comment: 2.5 nM CoraFluor-1-labeled anti-His6 antibody; 5 nM His6-FKBP12

    Reference: PMID