Formula:
avg. MolWt:
PAINS elements:
SMILES:
COC1=C(C=C(C=C1)CC[C@H](C2=CC(NC(CCC(NCCOCCOCCNC(NC3=CC=C(C(C(O)=O)=C3)C4=C(C(OC5=C4C=CC(O)=C5)=C6)C=CC6=O)=S)=O)=O)=CC=C2)OC([C@@H]7CCCCN7C(C(C(C)(CC)C)=O)=O)=O)OC
Store at:
Absorption:
Emission:
clogP:
Synthesis:
Contributing Lab:
Mazitschek Lab, Massachusetts General Hospital, Boston and Woo Lab, Harvard University, Boston
: 19.9
Z’: 0.86
: yes
KD:
Compound used for displacement:
d-FKPB1
IC50:
Comment: 2.5 nM CoraFluor-1-labeled anti-His6 antibody; 5 nM His6-FKBP12
Reference: PMID