|T000034, NCP409 (Thalidomide-FITC)
Compound Image

T000034

NCP409 (Thalidomide-FITC)

  • Description

    Formula:

    C42H37N5O13S

    avg. MolWt:

    851.85 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -20 °C

    Absorption:

    475 nm

    Emission:

    520 nm

    clogP:

    2.88
  • References

    Synthesis:

    Publication

    Contributing Lab:

    Mazitschek Lab, Massachusetts General Hospital, Boston

  • Experimental

    : 38.7

    Z’: 0.92

    : yes

    Tracer titration

    KD:

    46 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    dBET6

    IC50:

    12 nM
    raw data

    Comment: 1 nM CoraFluor-1-labeled anti-His6 antibody, 2.5 nM His6-CRBN/DDB1 complex

    Reference: PMID