Formula:
avg. MolWt:
PAINS elements:
SMILES:
O=C(NC1CC(C=CC=C2)=C2C1)C(N=CC=N3)=C3NC(N4CCC(NC(CCCCCNC(NC5=CC=C(C(C6=C7C=CC(C=C7OC8=C6C=CC(O)=C8)=O)=C5)C(O)=O)=S)=O)CC4)=O
Store at:
Absorption:
Emission:
clogP:
Synthesis:
Contributing Lab:
Mazitschek Lab, Massachusetts General Hospital, Boston
: 45.6
Z’: 0.89
: yes
KD:
Compound used for displacement:
NCP26
IC50:
Comment: HsProRS (996–1512), TR-FRET donor: CoraFluor-1
Reference: PMID