|T000025, MAT379
Compound Image

T000025

MAT379


  • Description

    Formula:

    C47H46N8O8S

    avg. MolWt:

    883.0 u

    PAINS elements:

    none detected

    SMILES:

    display
  • Properties

    Store at:

    -20 °C

    Absorption:

    475 nm

    Emission:

    520 nm

    clogP:

    6.32
  • References

    Synthesis:

    Contributing Lab:

    Mazitschek Lab, Massachusetts General Hospital, Boston

  • Experimental

    : 45.6

    Z’: 0.89

    : yes

    Tracer titration

    KD:

    220 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    NCP26

    IC50:

    244 nM
    raw data

    Comment: HsProRS (996–1512), TR-FRET donor: CoraFluor-1

    Reference: PMID