|T000022, BRD Tracer-02 (CS1810C20)

T000022

BRD Tracer-02 (CS1810C20)

Description

Formula:

C₃₃H₃₃BF₂N₁₀O₅S

avg. MolWt:

730.57 u

PAINS elements:

none detected

SMILES:

display

Properties

Store at:

-80 °C

Absorption:

450 nm

Emission:

590 nm

clogP:

4.07
References

Contributing Lab:

Promega Corp., Madison

Vendor:

Promega
Experimental

: 4.37

Z’: 0.79

: yes

Tracer titration

KD_app:

251 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

725 nM

raw data

Comment: NLuc-BRD2

Reference: PMID

: 3.65

Z’: 0.81

: yes

Tracer titration

KD_app:

588 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

2 µM

raw data

Comment: NLuc-BRD2(66-186)

: 4.43

Z’: 0.79

: yes

Tracer titration

KD_app:

615 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

2 µM

raw data

Comment: NLuc-BRD2(332-453)

: 5.59

Z’: 0.86

: yes

Tracer titration

KD_app:

359 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

531 nM

raw data

Comment: NLuc-BRD3

Reference: PMID

: 9.88

Z’: 0.85

: yes

Tracer titration

KD_app:

523 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

647 nM

raw data

Comment: NLuc-BRD3(20-148)

: 9.86

Z’: 0.9

: yes

Tracer titration

KD_app:

529 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

403 nM

raw data

Comment: NLuc-BRD3(299-420)

: 5.62

Z’: 0.84

: yes

Tracer titration

KD_app:

293 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

283 nM

raw data

Comment: NLuc-BRD4

Reference: PMID

: 7.5

Z’: 0.92

: yes

Tracer titration

KD_app:

555 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

93 nM

raw data

Comment: NLuc-BRD4(44-168)

: 13.4

Z’: 0.94

: yes

Tracer titration

KD_app:

194 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

274 nM

raw data

Comment: NLuc-BRDT

Reference: PMID

: 17.93

Z’: 0.92

: yes

Tracer titration

KD_app:

293 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

396 nM

raw data

Comment: NLuc-BRDT(13-139)

: 1.5

Z’: 0.74

: yes

Tracer titration

KD_app:

168 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

378 nM

raw data

Comment: TAF1-NLuc

: 4.5

Z’: 0.87

: yes

Tracer titration

KD_app:

198 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

203 nM

raw data

Comment: NLuc-TAF1-BD1-BD2 (1384-1638)

: 7.9

Z’: 0.92

: yes

Tracer titration

KD_app:

196 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

263 nM

raw data

Comment: NLuc-TAF1-BD2 (1515-1669)

: 1.7

Z’: 0.85

: yes

Tracer titration

KD_app:

271 nM

raw data

Tracer displacement

i

Compound used for displacement:

Bromosporine

EC₅₀:

1 µM

raw data

Comment: TAF1L-NLuc