|T000018, CRBN Tracer
Compound Image

T000018

CRBN Tracer

  • Properties

    Store at:

    -80 °C

    Absorption:

    450 nm

    Emission:

    590 nm
  • References

    Contributing Lab:

    Promega Corp., Madison

    Vendor:

    Promega
  • Experimental

    : 5.2

    Z’: 0.71

    : yes

    Tracer titration

    KDapp:

    305 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Lenalidomide

    EC50:

    112 nM
    raw data

    Comment: NLuc-CRBN + DDB1

    Reference: source

    : 3.3

    Z’: 0.79

    : yes

    Tracer titration

    KD:

    87 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    Lenalidomide

    IC50:

    174 nM
    raw data

    Comment: NLuc-CRBN + DDB1

    Reference: source