|T000015, p62-LIR Tracer
Compound Image

T000015

p62-LIR Tracer


  • Description

    Formula:

    C110H155N26O35+

    avg. MolWt:

    2401.6 u

    SMILES:

    display

    BILN:

    S-D-N-S-S-G-G-D-D-D-W-T-H-L-S-S-K-K(Cy5)
  • Properties

    Store at:

    -20 °C

    Absorption:

    590 nm

    Emission:

    675 nm

    clogP:

    -8.77
  • References

    Contributing Lab:

    Knapp Lab, University of Frankfurt

  • Experimental

    : 1.9

    Z’: 0.6

    : yes

    Protein titration

    KD:

    3443 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled p62-LIR peptide

    IC50:

    18 µM
    raw data

    Comment: use 30 nM of the p62-LIR peptide tracer

    Reference: source

    : 1.9

    Z’: 0.6

    : yes

    Protein titration

    KD:

    2495 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled p62-LIR peptide

    IC50:

    14 µM
    raw data

    Comment: use 30 nM of the p62-LIR peptide tracer

    Reference: source

    : 1.5

    Z’: 0.5

    : yes

    Protein titration

    KD:

    > 10 µM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled p62-LIR peptide

    IC50:

    46 µM
    raw data

    Comment: use 30 nM of the p62-LIR peptide tracer

    Reference: source

    : 1.5

    Z’: 0.8

    : yes

    Protein titration

    KD:

    7687 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled p62-LIR peptide

    IC50:

    17 µM
    raw data

    Comment: use 30 nM of the p62-LIR peptide tracer

    Reference: source

    : 1.6

    Z’: 0.7

    : yes

    Protein titration

    KD:

    5091 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled p62-LIR peptide

    IC50:

    19 µM
    raw data

    Comment: use 30 nM of the p62-LIR peptide tracer

    Reference: source

    : 1.5

    Z’: 0.6

    : yes

    Protein titration

    KD:

    7279 nM
    ...
    raw data
    Tracer displacement
    i

    Compound used for displacement:

    unlabelled p62-LIR peptide

    IC50:

    32 µM
    raw data

    Comment: use 30 nM of the p62-LIR peptide tracer

    Reference: source