|T000010, SRPK Tracer

Compound Image

T000010

SRPK Tracer

Description

Formula:

C₄₆H₅₂BF₂N₁₁O₇S

avg. MolWt:

951.87 u

PAINS elements:

none detected

SMILES:

display

Properties

Store at:

-80 °C

Absorption:

450 nm

Emission:

590 nm

clogP:

4.61
References

Synthesis:

Publication

Contributing Lab:

Knapp Lab, University of Frankfurt
Experimental

: 2.7

Z’: 0.6

: yes

Tracer titration

KD_app:

4285 nM

raw data

Tracer displacement

i

Compound used for displacement:

MSC-1186

EC₅₀:

81 nM

raw data

Comment: SRPK1-NLuc

Reference: PMID

: 4.0

Z’: 0.6

: yes

Tracer titration

K_D:

5054 nM

raw data

Tracer displacement

i

Compound used for displacement:

MSC-1186

IC₅₀:

90 nM

raw data

Comment: SRPK1-NLuc

Reference: PMID

: 1.7

Z’: 0.6

: yes

Tracer titration

KD_app:

1975 nM

raw data

Tracer displacement

i

Compound used for displacement:

MSC-1186

EC₅₀:

25 nM

raw data

Comment: NLuc-SRPK2

Reference: PMID

: 1.8

Z’: 0.5

: yes

Tracer titration

K_D:

1680 nM

raw data

Tracer displacement

i

Compound used for displacement:

MSC-1186

IC₅₀:

866 nM

raw data

Comment: NLuc-SRPK2

Reference: PMID

: 2.6

Z’: 0.5

: yes

Tracer titration

KD_app:

5815 nM

raw data

Tracer displacement

i

Compound used for displacement:

MSC-1186

EC₅₀:

29 nM

raw data

Comment: NLuc-SRPK3

Reference: PMID

: 4.2

Z’: 0.6

: yes

Tracer titration

K_D:

694 nM

raw data

Tracer displacement

i

Compound used for displacement:

MSC-1186

IC₅₀:

31 nM

raw data

Comment: NLuc-SRPK3

Reference: PMID