|T000001, IAP Tracer

Compound Image

T000001

IAP Tracer

Description

Formula:

C₄₈H₅₉BF₂N₈O₇S

avg. MolWt:

940.92 u

PAINS elements:

none detected

SMILES:

display

Properties

Store at:

-80 °C

Absorption:

450 nm

Emission:

590 nm

clogP:

5.65
References

Synthesis:

Publication

Contributing Lab:

Promega Corp., Madison and Knapp Lab, Knapp Lab, University of Frankfurt
Experimental

: 7.0

Z’: 0.6

: yes

Tracer titration

KD_app:

17 nM

raw data

Tracer displacement

i

Compound used for displacement:

LCL161

EC₅₀:

5 nM

raw data

Reference: PMID

: 8.0

Z’: 0.7

: yes

Tracer titration

KD_app:

163 nM

raw data

Tracer displacement

i

Compound used for displacement:

LCL161

EC₅₀:

15 nM

raw data

Reference: PMID

: 10.8

Z’: 0.7

: yes

Tracer titration

KD_app:

240 nM

raw data

Tracer displacement

i

Compound used for displacement:

LCL161

EC₅₀:

26 nM

raw data

Reference: PMID

: 42.9

Z’: 0.8

: yes

Tracer titration

KD_app:

2713 nM

raw data

Tracer displacement

i

Compound used for displacement:

LCL161

EC₅₀:

212 nM

raw data

Reference: PMID

: 4.3

Z’: 0.6

: yes

Tracer titration

KD_app:

38 nM

raw data

Tracer displacement

i

Compound used for displacement:

LCL161

EC₅₀:

15 nM

raw data

Reference: PMID